• squaresinger@lemmy.world
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    1 month ago

    I would be seriously tempted to try this stuff as someone who doesn’t suffer from CF just to see what it would be like.

    The answer is: Nothing. It would literally do nothing for you.

    The underlying issue of Cystic Fibrosis is that (depending on the mutation) too few or non-working ion channels are produced within the cells, which means that the body cannot regulate salt concentrations and due to that water concentrations in different mucuses in the body.

    CF modulators like Trikafta fix these issues by making sure that working ion channels are produced in sufficient amounts. If your body already produces enough ion channels in sufficient amounts, using CF modulators does nothing but waste an incredible amount of money (~€350k per year).

    On the flip side, the side effects are also not very strong at all, neither for healthy people nor for CF patients. In fact, the initial trials for Trikafta said that the placebo control group had more side effects than the people who got the medication.